Sebacic Acid, CAS No: 111-20-6

• Customization: Available
• CAS No.: 111-20-6
• Formula: C10h18o4
• Model NO.: CAS NO: 111-20-6
• Status: Solid Catalyst
• Response Type: Hydrogenation
• Classification: Homogeneous Catalysts
• Usage: Positive Catalyst
• Effect Size: Promoter Catalysts
• Manufacturing Method: Mechanical Mixing
• Application Industry: Medical Science
• Density: 1.1±0.1 g/cm3
• Molecular Weight: 202.247
• Boiling Point: 374.3±0.0 °c at 760 Mmhg
• Melting Point: 133-137 °c(Lit.)
• Specification: 25KG/BAG
• Trademark: LABEYOND
• Origin: China
• HS Code: 2917131000

Product Description

Sebacic acid

 

Sebacic acid is a naturally occurring dicarboxylic acid with the chemical formula HO₂C(CH₂)₈CO₂H. It is a white flake or powdered solid. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid is a derivative of castor oil.

In the industrial setting, sebacic acid and its homologues such as azelaic acid can be used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc.

It can be used as a surfactant in the lubricating oil industry to increase the antirust properties of lubricating oils on metals.

Production
Sebacic acid is produced from castor oil by cleavage of ricinoleic acid, which is obtained from castor oil. Octanol & glycerin is a byproduct.

It can also be obtained from decalin via the tertiary hydroperoxide, which gives cyclodecenone, a precursor to sebacic acid.

Potential medical significance
Sebum is a secretion by skin sebaceous glands. It is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%).Included in the free fatty acid secretions in sebum are polyunsaturated fatty acids and sebacic acid. Sebacic acid is also found in other lipids that coat the skin surface. Human neutrophils can convert sebacic acid to its 5-oxo analog, i.e., 5-oxo-6E,8Z-octadecenoic acid, a structural analog of 5-oxo-eicosatetraenoic acid and like this oxo-eicosatetraenoic acid is an exceptionally potent activator of eosinophils, monocytes, and other pro-inflammatory cells from humans and other species. This action is mediated by the OXER1 receptor on these cells. It is suggested that sebacic acid is converted to its 5-oxo analog during, and thereby stimulates pro-inflammatory cells to contribute to the worsening of, various inflammatory skin conditions.